Review: The Triple Negative Breast Cancer Foundation

Breast Cancer, Cancer Websites — By on September 12, 2008 at 8:08 am

Triple negative breast cancer accounts for approximately 15% of all breast cancer cases. It occurs most often in African American and younger women.

The Triple Negative Breast Cancer Foundation is dedicated to the advancement for research for “triple negative breast cancer and is devoted to finding targeted treatment for it.

It is now commonly understood that breast cancer is not one form of cancer, but many different “subtypes” of cancer. These subtypes of breast cancer are generally diagnosed based upon the presence, or lack of, three “receptors” known to fuel most breast cancers: estrogen receptors, progesterone receptors and human epidermal growth factor receptor 2 (HER2).

The most successful treatments for breast cancer target these receptors. Unfortunately, none of these receptors are found in women with triple negative breast cancer. In other words, a triple negative breast cancer diagnosis means that the offending tumor is estrogen receptor-negative; progesterone receptor-negative and HER2-negative, thus giving rise to the name “triple negative breast cancer.”

On a positive note, this type of breast cancer is typically responsive to chemotherapy but because of its triple negative status, triple negative tumors generally do not respond to receptor targeted treatments.

Depending on the stage of its diagnosis, triple negative breast cancer can be particularly aggressive, and more likely to recur than other subtypes of breast cancer. Because it is a recently recognized form of breast cancer, there is very little known about its pathology.

Since its inception in 2006, TNBC has raised over $240,000 to further this mission.
To get involved or to find out more information, please visit: The Triple Negative Breast Cancer Foundation

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