Groundbreaking DNA Study Set To Create New Therapies For Deadly Diseases

Cancer Research, News — By on November 6, 2008 at 9:08 am

Scientists have taken a major step in cell research by unravelling how stem cells differentiate and what are the corresponding changes that take place during DNA replication and reorganization.

The groundbreaking study led by David M. Gilbert, an eminent molecular biologist at Florida State University and the study’s principal investigator,
has now taken scientists a step closer to the central goal of stem cell therapy- to successfully convert adult tissue back to an embryo-like state so that it can be used to regenerate or replace damaged tissue.

Stem cell therapies also holds promise of developing treatments or cures for cancer, Parkinson’s disease, multiple sclerosis, spinal cord injuries and a host of other devastating disorders.

Gilbert added: “We know that all the information (DNA) required to take on the identity of any tissue type is present in every cell, because we already can, albeit very inefficiently, create whole animals from adult tissue through cloning.”

The study, titled “Global Reorganization of Replication Domains During Embryonic Stem Cell Differentiation,” has been published in the latest edition of PLoS Biology.

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