Busted: Mutant Genes Causing Lung Cancer

Cancer Research, News — By on October 27, 2008 at 3:15 pm

Scientists in the United States have identified 26 genes whose mutation plays a role in the commonest form of lung cancer, including genes that may be receptive to novel drugs or existing treatments used to tackle other tumors. The haul, reported on Wednesday in the British-based science journal Nature, doubles the tally of genes fingered in lung adenocarcinoma, which accounts for around 40 percent of cases of lung cancer.

Nearly nine out of every 10 cases occur among smokers or former heavy smokers. Many new targets for therapy of this deadly disease have been uncovered.  The work entailed taking samples of lung tissue from 188 cancer patients in the United States and looking at 623 suspect genes.

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