Vaccine Against Brain Cancer

News — By on September 1, 2010 at 6:52 pm

(Reuters) – A small, early-stage trial of a therapeutic brain cancer vaccine developed by ImmunoCellular Therapeutics Ltd showed that nearly half the patients were alive without their cancer worsening 18 months after diagnosis. The Phase 1 trial involved 16 patients with glioblastoma multiforme, the most common and deadly form of brain cancer.

They were treated with ICT-107, an experimental dendritic cell based cancer vaccine, following the standard care of surgery, radiation and chemotherapy.

“We are targeting specific antigens that are on cancer stem cells … the only population of cells that can really propagate a tumor,” said Dr. John Yu, director of surgical neuro-oncology at Cedars-Sinai Medical Center in Los Angeles and ImmunoCellular’s chief scientific officer.

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