Large Study Documents How P53 Mutations Link To High-Grade Breast Cancer, Poor Outcomes

News — By on April 20, 2009 at 2:00 am

In what is believed to be the largest study of its kind in the US, researchers have found that almost 26 percent of women studied who have breast cancer have mutations in a gene important in controlling cell growth and death, and that patients with mutations in this gene – known as p53 – had poorer outcomes including a significantly increased risk of death from the cancer.

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